RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
DEFA4
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
Pulmonary function testing; Quality characterization; Gene ontology and functional network analysis etc.
Target
NA
Pathway
NA
PubMed ID
Title
The peripheral blood transcriptome identifies the presence and extent of disease in idiopathic pulmonary fibrosis
Year
2012
Function
"Between the mild and severe IPF cohort , and between normal and severe disease, there is up-regulation of several other host defense genes including defensin A4 (DEFA4), cathelicidin antimicrobial peptide (CAMP), cathespin G (CTSG), and down-regulation of immunoglobulin heavy chain constant mu (IGHM)."